Wan 2.2 S2V 14B (speech to video) on AMD EPYC 7002 / 7003 series NAS (512 GB)

Can the AMD EPYC 7002 / 7003 series NAS (512 GB) run Wan 2.2 S2V 14B (speech to video)?

Barely: it runs very slowly

Very slow. At FP16 it needs about 50.4 GB of 471 GB usable, with an estimated speed of 11.4 h.

Best precision: FP16
Memory mode: Everything on GPU
Time per clip: 11.4 h
Output: 832×480, 81 frames, 40 steps

Download Wan 2.2 S2V 14B (speech to video)

Quantized files · GGUF for ComfyUI

Smaller GGUF versions for ComfyUI (with the ComfyUI-GGUF node). No sign-in needed; the model’s license still applies.

huggingface.co/QuantStack/Wan2.2-S2V-14B-GGUF (opens in a new tab)

Original weights · Hugging Face

Full-precision files from Alibaba, for fine-tuning, vLLM, Transformers, Diffusers or ComfyUI.

huggingface.co/Wan-AI/Wan2.2-S2V-14B (opens in a new tab)

No sign-in needed.

Official repo · GitHub

Reference code, inference scripts and docs from Alibaba. The weights themselves download from Hugging Face.

github.com/Wan-Video/Wan2.2 (opens in a new tab)

git clone https://github.com/Wan-Video/Wan2.2

Links checked 1 day ago against Hugging Face, Ollama and GitHub.

How it’s rated

Quality 76Great quality (A) · 76 of 100: how capable the model is at FP16, whatever it runs on. Match score 62/100 (quality, fit, speed and memory use) sets the ranking.: How capable the model itself is at FP16, from its editorial quality tier scaled by the quantization or precision. It’s the same on any hardware that runs this variant. Scale: A+ 85+ · A 70+ · B 55+ · C 40+ · D under 40.
Runs Very slow: How well it runs on the AMD EPYC 7002 / 7003 series NAS (512 GB): speed, capped by how well it fits in memory. Runs great: 30+ tokens/s (or near the image, video or decision speed target) · Runs well: 10+ tokens/s · Slow: 3+ tokens/s · Very slow: under 3 · Won’t run: doesn’t fit even with offload. A tight fit or RAM offload caps it at Runs well; heavy offload caps it at Slow.

Match score

To order lists, each result also gets a match score out of 100 from four parts. It favors the most capable model that still runs well.

Model qualityEditorial quality tier of the model, scaled by the quantization or precision used.	34.2 / 45
Memory fitFull marks when the model fits in the share of the NAS’s memory that models can use (the rest stays with the NAS system and its storage services); fewer when it goes past that limit.	25.0 / 25
SpeedGeneration speed against a 40 tokens/s target for LLMs, or render time against a target for image and video.	1.0 / 15
Memory useRewards using the memory you have, so a bigger, better variant beats a tiny one that leaves most memory idle.	2.5 / 15
Match score	62.7 / 100

The match score orders results; it is not shown as a grade. Quality and Runs are the two ratings in the tables.

Every precision on the AMD EPYC 7002 / 7003 series NAS (512 GB)

Quant	Memory needed	Available	Speed	Memory mode	Runs	Quality	Download
`FP16`	50.4 GB	471 GB	11.4 h	Everything on GPU	Very slow	76Great quality (A) · 76 of 100: how capable the model is at FP16, whatever it runs on. Match score 62/100 (quality, fit, speed and memory use) sets the ranking.	Original weights (opens in a new tab)
`FP8`	28.1 GB	471 GB	10.3 h	Everything on GPU	Very slow	74Great quality (A) · 74 of 100: how capable the model is at FP8, whatever it runs on. Match score 60/100 (quality, fit, speed and memory use) sets the ranking.	Original weights (opens in a new tab)
`Q8 GGUF`	29.3 GB	471 GB	13.1 h	Everything on GPU	Very slow	75Great quality (A) · 75 of 100: how capable the model is at Q8 GGUF, whatever it runs on. Match score 61/100 (quality, fit, speed and memory use) sets the ranking.	GGUF (opens in a new tab)
`Q4 GGUF`	21.6 GB	471 GB	13.7 h	Everything on GPU	Very slow	70Great quality (A) · 70 of 100: how capable the model is at Q4 GGUF, whatever it runs on. Match score 58/100 (quality, fit, speed and memory use) sets the ranking.	GGUF (opens in a new tab)

Other hardware that runs it

74Great quality (A) · 74 of 100: how capable the model is at FP8, whatever it runs on. Match score 73/100 (quality, fit, speed and memory use) sets the ranking. NVIDIA RTX PRO 6000 Blackwell FP8 · 11.0 min · Runs well
76Great quality (A) · 76 of 100: how capable the model is at FP16, whatever it runs on. Match score 81/100 (quality, fit, speed and memory use) sets the ranking. NVIDIA H100 80GB SXM FP16 · 11.6 min · Runs well
76Great quality (A) · 76 of 100: how capable the model is at FP16, whatever it runs on. Match score 81/100 (quality, fit, speed and memory use) sets the ranking. NVIDIA H800 80GB SXM FP16 · 11.6 min · Runs well
76Great quality (A) · 76 of 100: how capable the model is at FP16, whatever it runs on. Match score 78/100 (quality, fit, speed and memory use) sets the ranking. NVIDIA GH200 Grace Hopper (96 GB GPU) FP16 · 11.6 min · Runs well
76Great quality (A) · 76 of 100: how capable the model is at FP16, whatever it runs on. Match score 75/100 (quality, fit, speed and memory use) sets the ranking. NVIDIA H200 141GB SXM FP16 · 11.6 min · Runs well
76Great quality (A) · 76 of 100: how capable the model is at FP16, whatever it runs on. Match score 73/100 (quality, fit, speed and memory use) sets the ranking. NVIDIA B200 FP16 · 10.2 min · Runs well

Estimates come from published hardware specs and our open formulas, not from running the model on your machine. Real speed varies with runtime, drivers and settings. Numbers marked “Measured” come from a linked benchmark.