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Can the AMD Ryzen AI Max+ 395 (128 GB) run Qwen3-VL 235B-A22B Instruct?

59 ptsGood (B) · 59 of 100 points: Model quality 28.0/45, Memory fit 10.0/25, Speed 6.9/15, Memory use 15.0/15

Yes, with part of the model in system RAM

Runs with offload. At Q2_K it needs about 104 GB of 96.0 GB usable, with an estimated speed of 8.6 tok/s.

Best quant
Q2_K
Generation speed
8.6 tok/s
Prompt processing
1,674 tok/s
First token (1K prompt)
0.6 s
Largest safe context
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Download Qwen3-VL 235B-A22B Instruct

Quickest · Ollama

One command downloads a ready-to-run version and starts a chat.

ollama run qwen3-vl:235b

Get Ollama at ollama.com/download (opens in a new tab) · model page (opens in a new tab)

Quantized files · GGUF

Works in LM Studio, llama.cpp, Jan and Ollama. No sign-in needed.

huggingface.co/Qwen/Qwen3-VL-235B-A22B-Instruct-GGUF (opens in a new tab)

ollama run hf.co/Qwen/Qwen3-VL-235B-A22B-Instruct-GGUF

Original weights · Hugging Face

Full-precision files from Alibaba, for fine-tuning, vLLM, Transformers.

huggingface.co/Qwen/Qwen3-VL-235B-A22B-Instruct (opens in a new tab)

No sign-in needed.

Links checked 1 week ago against Hugging Face, Ollama and GitHub.

How the B grade is scored

Every result gets up to 100 points from four parts. The points decide the letter grade.

Model qualityEditorial quality tier of the model, scaled by the quantization or precision used.28.0 / 45
Memory fitFull marks when everything sits in GPU or unified memory; fewer when part spills to system RAM.10.0 / 25
SpeedGeneration speed against a 40 tokens/s target for LLMs, or render time against a target for image and video.6.9 / 15
Memory useRewards using the memory you have, so a bigger, better variant beats a tiny one that leaves most memory idle.15.0 / 15
Total60.0 / 10059 ptsGood (B) · 59 of 100 points: Model quality 28.0/45, Memory fit 10.0/25, Speed 6.9/15, Memory use 15.0/15

Grade scale: S 85+ · A 72+ · B 58+ · C 42+ · D 25+ · F under 25 points.

Every quantization on the AMD Ryzen AI Max+ 395 (128 GB)

Quant Memory needed Available Speed Fit Grade · points Download
Q2_K 104 GB 96.0 GB 8.6 tok/s Runs with offload 59 ptsGood (B) · 59 of 100 points: Model quality 28.0/45, Memory fit 10.0/25, Speed 6.9/15, Memory use 15.0/15 GGUF files (opens in a new tab)
Q3_K_M 125 GB 96.0 GB — Won't run 10 ptsWon't run (F) · 10 of 100 points: Model quality 10.1/45, Memory fit 0.0/25, Speed 0.0/15, Memory use 0.0/15 GGUF files (opens in a new tab)
Q4_K_M 154 GB 96.0 GB — Won't run 11 ptsWon't run (F) · 11 of 100 points: Model quality 11.4/45, Memory fit 0.0/25, Speed 0.0/15, Memory use 0.0/15 GGUF · part 1 of 3 (opens in a new tab)
Q5_K_M 177 GB 96.0 GB — Won't run 11 ptsWon't run (F) · 11 of 100 points: Model quality 11.7/45, Memory fit 0.0/25, Speed 0.0/15, Memory use 0.0/15 GGUF files (opens in a new tab)
Q6_K 203 GB 96.0 GB — Won't run 11 ptsWon't run (F) · 11 of 100 points: Model quality 11.9/45, Memory fit 0.0/25, Speed 0.0/15, Memory use 0.0/15 GGUF files (opens in a new tab)
Q8_0 260 GB 96.0 GB — Won't run 12 ptsWon't run (F) · 12 of 100 points: Model quality 12.0/45, Memory fit 0.0/25, Speed 0.0/15, Memory use 0.0/15 GGUF · part 1 of 6 (opens in a new tab)
F16 481 GB 96.0 GB — Won't run 12 ptsWon't run (F) · 12 of 100 points: Model quality 12.0/45, Memory fit 0.0/25, Speed 0.0/15, Memory use 0.0/15 GGUF · part 1 of 10 (opens in a new tab) Original weights (opens in a new tab)

Memory figures assume 8K of context. Longer conversations or documents grow the KV cache.

Other hardware that runs it

Estimates come from published hardware specs and our open formulas, not from running the model on your machine. Real speed varies with runtime, drivers and settings. Numbers marked “Measured” come from a linked benchmark.