Qwen2 72B Instruct on AMD Ryzen AI Max+ 395 (128 GB)
Can the AMD Ryzen AI Max+ 395 (128 GB) run Qwen2 72B Instruct?
Yes, it runs well
Runs well. At Q6_K it needs about 70.6 GB of 96.0 GB usable, with an estimated speed of 2.6 tok/s.
- Best quant
Q6_K- Generation speed
- 2.6 tok/s
- Prompt processing
- 507 tok/s
- First token (1K prompt)
- 2.0 s
- Largest safe context
- 32K
Download Qwen2 72B Instruct
Recommended for the AMD Ryzen AI Max+ 395 (128 GB): Q6_K. Every other quantization has its own download link in the table below.
Quickest · Ollama
One command downloads a ready-to-run version and starts a chat.
ollama run qwen2:72b-instruct-q6_KQuantized files · GGUF
Works in LM Studio, llama.cpp, Jan and Ollama. No sign-in needed.
Download the Q6_K file (opens in a new tab)
huggingface.co/Qwen/Qwen2-72B-Instruct-GGUF (opens in a new tab)
ollama run hf.co/Qwen/Qwen2-72B-Instruct-GGUF:Q6_KOriginal weights · Hugging Face
Full-precision files from Alibaba, for fine-tuning, vLLM, Transformers.
How the A grade is scored
Every result gets up to 100 points from four parts. The points decide the letter grade.
| Model quality | 28.5 / 45 | |
|---|---|---|
| Memory fit | 25.0 / 25 | |
| Speed | 3.8 / 15 | |
| Memory use | 15.0 / 15 | |
| Total | 72.3 / 100 | 72 ptsGreat (A) · 72 of 100 points: Model quality 28.5/45, Memory fit 25.0/25, Speed 3.8/15, Memory use 15.0/15 |
Every quantization on the AMD Ryzen AI Max+ 395 (128 GB)
| Quant | Memory needed | Available | Speed | Fit | Grade · points | Download |
|---|---|---|---|---|---|---|
Q2_K | 40.0 GB | 96.0 GB | 6.1 tok/s | Runs well | 60 ptsGood (B) · 60 of 100 points: Model quality 20.2/45, Memory fit 25.0/25, Speed 5.9/15, Memory use 9.6/15 | GGUF (opens in a new tab) |
Q3_K_M | 46.6 GB | 96.0 GB | 4.8 tok/s | Runs well | 65 ptsGood (B) · 65 of 100 points: Model quality 24.2/45, Memory fit 25.0/25, Speed 5.2/15, Memory use 11.2/15 | GGUF (opens in a new tab) |
Q4_K_M | 55.3 GB | 96.0 GB | 3.7 tok/s | Runs well | 70 ptsGood (B) · 70 of 100 points: Model quality 27.4/45, Memory fit 25.0/25, Speed 4.6/15, Memory use 13.3/15 | GGUF (opens in a new tab) |
Q5_K_M | 62.6 GB | 96.0 GB | 3.1 tok/s | Runs well | 72 ptsGreat (A) · 72 of 100 points: Model quality 27.9/45, Memory fit 25.0/25, Speed 4.2/15, Memory use 15.0/15 | GGUF · part 1 of 2 (opens in a new tab) |
Q6_K | 70.6 GB | 96.0 GB | 2.6 tok/s | Runs well | 72 ptsGreat (A) · 72 of 100 points: Model quality 28.5/45, Memory fit 25.0/25, Speed 3.8/15, Memory use 15.0/15 | GGUF · part 1 of 2 (opens in a new tab) |
Q8_0 | 88.0 GB | 96.0 GB | 1.9 tok/s | Tight fit | 71 ptsGood (B) · 71 of 100 points: Model quality 28.8/45, Memory fit 24.0/25, Speed 3.3/15, Memory use 15.0/15 | GGUF · part 1 of 2 (opens in a new tab) |
F16 | 156 GB | 96.0 GB | — | Won't run | 8 ptsWon't run (F) · 8 of 100 points: Model quality 8.6/45, Memory fit 0.0/25, Speed 0.0/15, Memory use 0.0/15 | GGUF · part 1 of 4 (opens in a new tab) Original weights (opens in a new tab) |
Memory figures assume 8K of context. Longer conversations or documents grow the KV cache.
Other hardware that runs it
- 78 ptsGreat (A) · 78 of 100 points: Model quality 27.4/45, Memory fit 25.0/25, Speed 13.0/15, Memory use 12.6/15 NVIDIA RTX PRO 6000 Blackwell
- 74 ptsGreat (A) · 74 of 100 points: Model quality 28.5/45, Memory fit 25.0/25, Speed 5.6/15, Memory use 15.0/15 Apple M4 Max (128 GB)
- 72 ptsGreat (A) · 72 of 100 points: Model quality 28.5/45, Memory fit 25.0/25, Speed 4.2/15, Memory use 14.4/15 NVIDIA GB10 (128 GB)
- 70 ptsGood (B) · 70 of 100 points: Model quality 24.2/45, Memory fit 24.0/25, Speed 7.6/15, Memory use 15.0/15 Apple M4 Max (64 GB)
- 69 ptsGood (B) · 69 of 100 points: Model quality 27.4/45, Memory fit 25.0/25, Speed 8.1/15, Memory use 9.5/15 Apple M2 Ultra (192 GB)
Estimates come from published hardware specs and our open formulas, not from running the model on your machine. Real speed varies with runtime, drivers and settings. Numbers marked “Measured” come from a linked benchmark.