Qwen2.5 72B Instruct on AMD EPYC 7002 / 7003 series NAS (32 GB)

Can the AMD EPYC 7002 / 7003 series NAS (32 GB) run Qwen2.5 72B Instruct?

No, it doesn’t fit

No. Qwen2.5 72B Instruct needs about 34.5 GB even at Q2_K; the AMD EPYC 7002 / 7003 series NAS (32 GB) has 26.2 GB usable.

Download Qwen2.5 72B Instruct

Recommended: Q2_K. Every other quantization has its own download link in the table below.

Quickest · Ollama

One command downloads a ready-to-run version and starts a chat.

Get Ollama at ollama.com/download (opens in a new tab) · model page (opens in a new tab)

ollama run qwen2.5:72b-instruct-q2_K

Quantized files · GGUF

Works in LM Studio, llama.cpp, Jan and Ollama. No sign-in needed.

Download the Q2_K file (opens in a new tab)

huggingface.co/Qwen/Qwen2.5-72B-Instruct-GGUF (opens in a new tab)

ollama run hf.co/Qwen/Qwen2.5-72B-Instruct-GGUF:Q2_K

Original weights · Hugging Face

Full-precision files from Alibaba, for fine-tuning, vLLM, Transformers.

huggingface.co/Qwen/Qwen2.5-72B-Instruct (opens in a new tab)

No sign-in needed.

Official repo · GitHub

Reference code, inference scripts and docs from Alibaba. The weights themselves download from Hugging Face.

github.com/QwenLM/Qwen3 (opens in a new tab)

Qwen’s main repo, renamed from Qwen2.5 to Qwen3; it still documents Qwen2.5.

git clone https://github.com/QwenLM/Qwen3

Links checked 1 day ago against Hugging Face, Ollama and GitHub.

How it’s rated

Quality 51Fair quality (C) · 51 of 100: how capable the model is at Q2_K, whatever it runs on. Match score 6/100 (quality, fit, speed and memory use) sets the ranking.: How capable the model itself is at Q2_K, from its editorial quality tier scaled by the quantization or precision. It’s the same on any hardware that runs this variant. Scale: A+ 85+ · A 70+ · B 55+ · C 40+ · D under 40.
Runs Won't run: How well it runs on the AMD EPYC 7002 / 7003 series NAS (32 GB): speed, capped by how well it fits in memory. Runs great: 30+ tokens/s (or near the image, video or decision speed target) · Runs well: 10+ tokens/s · Slow: 3+ tokens/s · Very slow: under 3 · Won’t run: doesn’t fit even with offload. A tight fit or RAM offload caps it at Runs well; heavy offload caps it at Slow.

Match score

To order lists, each result also gets a match score out of 100 from four parts. It favors the most capable model that still runs well.

Model qualityEditorial quality tier of the model, scaled by the quantization or precision used.	6.9 / 45
Memory fitFull marks when the model fits in the share of the NAS’s memory that models can use (the rest stays with the NAS system and its storage services); fewer when it goes past that limit.	0.0 / 25
SpeedGeneration speed against a 40 tokens/s target for LLMs, or render time against a target for image and video.	0.0 / 15
Memory useRewards using the memory you have, so a bigger, better variant beats a tiny one that leaves most memory idle.	0.0 / 15
Match score	6.9 / 100

The match score orders results; it is not shown as a grade. Quality and Runs are the two ratings in the tables.

It doesn’t fit, so only a reduced share of the quality points counts and fit, speed and memory use score zero.

Every quantization on the AMD EPYC 7002 / 7003 series NAS (32 GB)

Quant	Memory needed	Available	Speed	Runs	Quality	Download
`Q2_K`	34.5 GB	26.2 GB	—	Won't run	51Fair quality (C) · 51 of 100: how capable the model is at Q2_K, whatever it runs on. Match score 6/100 (quality, fit, speed and memory use) sets the ranking.	GGUF · part 1 of 7 (opens in a new tab)
`Q3_K_M`	41.0 GB	26.2 GB	—	Won't run	61Good quality (B) · 61 of 100: how capable the model is at Q3_K_M, whatever it runs on. Match score 8/100 (quality, fit, speed and memory use) sets the ranking.	GGUF · part 1 of 9 (opens in a new tab)
`Q4_K_M`	49.7 GB	26.2 GB	—	Won't run	69Good quality (B) · 69 of 100: how capable the model is at Q4_K_M, whatever it runs on. Match score 9/100 (quality, fit, speed and memory use) sets the ranking.	GGUF · part 1 of 12 (opens in a new tab)
`Q5_K_M`	57.0 GB	26.2 GB	—	Won't run	70Great quality (A) · 70 of 100: how capable the model is at Q5_K_M, whatever it runs on. Match score 9/100 (quality, fit, speed and memory use) sets the ranking.	GGUF · part 1 of 14 (opens in a new tab)
`Q6_K`	65.0 GB	26.2 GB	—	Won't run	72Great quality (A) · 72 of 100: how capable the model is at Q6_K, whatever it runs on. Match score 9/100 (quality, fit, speed and memory use) sets the ranking.	GGUF · part 1 of 16 (opens in a new tab)
`Q8_0`	82.4 GB	26.2 GB	—	Won't run	73Great quality (A) · 73 of 100: how capable the model is at Q8_0, whatever it runs on. Match score 9/100 (quality, fit, speed and memory use) sets the ranking.	GGUF · part 1 of 21 (opens in a new tab)
`F16`	151 GB	26.2 GB	—	Won't run	73Great quality (A) · 73 of 100: how capable the model is at F16, whatever it runs on. Match score 9/100 (quality, fit, speed and memory use) sets the ranking.	GGUF · part 1 of 42 (opens in a new tab) Original weights (opens in a new tab)

Memory figures assume 8K of context. Longer conversations or documents grow the KV cache.

Hardware that can run it

69Good quality (B) · 69 of 100: how capable the model is at Q4_K_M, whatever it runs on. Match score 81/100 (quality, fit, speed and memory use) sets the ranking. NVIDIA RTX PRO 6000 Blackwell Q4_K_M · 30.3 tok/s · Runs great
61Good quality (B) · 61 of 100: how capable the model is at Q3_K_M, whatever it runs on. Match score 74/100 (quality, fit, speed and memory use) sets the ranking. Apple M4 Max (64 GB) Q3_K_M · 10.3 tok/s · Runs well (tight fit)
69Good quality (B) · 69 of 100: how capable the model is at Q4_K_M, whatever it runs on. Match score 73/100 (quality, fit, speed and memory use) sets the ranking. Apple M2 Ultra (192 GB) Q4_K_M · 11.6 tok/s · Runs well
69Good quality (B) · 69 of 100: how capable the model is at Q4_K_M, whatever it runs on. Match score 71/100 (quality, fit, speed and memory use) sets the ranking. Apple M3 Ultra (256 GB) Q4_K_M · 11.9 tok/s · Runs well
61Good quality (B) · 61 of 100: how capable the model is at Q3_K_M, whatever it runs on. Match score 71/100 (quality, fit, speed and memory use) sets the ranking. Apple M4 Max (128 GB) Q3_K_M · 10.3 tok/s · Runs well
69Good quality (B) · 69 of 100: how capable the model is at Q4_K_M, whatever it runs on. Match score 69/100 (quality, fit, speed and memory use) sets the ranking. Apple M3 Ultra (512 GB) Q4_K_M · 11.9 tok/s · Runs well

Models that do run on the AMD EPYC 7002 / 7003 series NAS (32 GB)

88Excellent quality (A+) · 88 of 100: how capable the model is at Q4_K_M, whatever it runs on. Match score 93/100 (quality, fit, speed and memory use) sets the ranking. Qwen3.6 35B-A3B Q4_K_M · 40.2 tok/s
88Excellent quality (A+) · 88 of 100: how capable the model is at Q4_K_M, whatever it runs on. Match score 93/100 (quality, fit, speed and memory use) sets the ranking. MiniCPM-V 4.7 35B-A3B Q4_K_M · 40.2 tok/s
88Excellent quality (A+) · 88 of 100: how capable the model is at Q4_K_M, whatever it runs on. Match score 93/100 (quality, fit, speed and memory use) sets the ranking. Qwen3.5 35B-A3B Q4_K_M · 40.2 tok/s
87Excellent quality (A+) · 87 of 100: how capable the model is at Q4_K_M, whatever it runs on. Match score 93/100 (quality, fit, speed and memory use) sets the ranking. Nex N2 Mini (35B-A3B) Q4_K_M · 40.2 tok/s
87Excellent quality (A+) · 87 of 100: how capable the model is at Q4_K_M, whatever it runs on. Match score 93/100 (quality, fit, speed and memory use) sets the ranking. Gemma 4 26B-A4B Q4_K_M · 32.7 tok/s

Estimates come from published hardware specs and our open formulas, not from running the model on your machine. Real speed varies with runtime, drivers and settings. Numbers marked “Measured” come from a linked benchmark.