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Can the Apple M2 Pro (32 GB) run Qwen2.5 72B Instruct?

6 ptsWon't run (F) · 6 of 100 points: Model quality 6.9/45, Memory fit 0.0/25, Speed 0.0/15, Memory use 0.0/15

No, it doesn’t fit

No. Qwen2.5 72B Instruct needs about 34.1 GB even at Q2_K; the Apple M2 Pro (32 GB) has 21.4 GB usable.

Download Qwen2.5 72B Instruct

Recommended: Q2_K. Every other quantization has its own download link in the table below.

Quickest · Ollama

One command downloads a ready-to-run version and starts a chat.

ollama run qwen2.5:72b-instruct-q2_K

Get Ollama at ollama.com/download (opens in a new tab) · model page (opens in a new tab)

Quantized files · GGUF

Works in LM Studio, llama.cpp, Jan and Ollama. No sign-in needed.

Download the Q2_K file (opens in a new tab)

huggingface.co/Qwen/Qwen2.5-72B-Instruct-GGUF (opens in a new tab)

ollama run hf.co/Qwen/Qwen2.5-72B-Instruct-GGUF:Q2_K

Original weights · Hugging Face

Full-precision files from Alibaba, for fine-tuning, vLLM, Transformers.

huggingface.co/Qwen/Qwen2.5-72B-Instruct (opens in a new tab)

No sign-in needed.

Official repo · GitHub

Reference code, inference scripts and docs from Alibaba. The weights themselves download from Hugging Face.

github.com/QwenLM/Qwen3 (opens in a new tab)

git clone https://github.com/QwenLM/Qwen3

Qwen’s main repo, renamed from Qwen2.5 to Qwen3; it still documents Qwen2.5.

How the F grade is scored

Every result gets up to 100 points from four parts. The points decide the letter grade.

Model qualityEditorial quality tier of the model, scaled by the quantization or precision used.6.9 / 45
Memory fitFull marks when everything sits in GPU or unified memory; fewer when part spills to system RAM.0.0 / 25
SpeedGeneration speed against a 40 tokens/s target for LLMs, or render time against a target for image and video.0.0 / 15
Memory useRewards using the memory you have, so a bigger, better variant beats a tiny one that leaves most memory idle.0.0 / 15
Total6.9 / 1006 ptsWon't run (F) · 6 of 100 points: Model quality 6.9/45, Memory fit 0.0/25, Speed 0.0/15, Memory use 0.0/15

It doesn’t fit, so only a reduced share of the quality points counts and fit, speed and memory use score zero.

Grade scale: S 85+ · A 72+ · B 58+ · C 42+ · D 25+ · F under 25 points.

Every quantization on the Apple M2 Pro (32 GB)

Quant Memory needed Available Speed Fit Grade · points Download
Q2_K 34.1 GB 21.4 GB — Won't run 6 ptsWon't run (F) · 6 of 100 points: Model quality 6.9/45, Memory fit 0.0/25, Speed 0.0/15, Memory use 0.0/15 GGUF · part 1 of 7 (opens in a new tab)
Q3_K_M 40.6 GB 21.4 GB — Won't run 8 ptsWon't run (F) · 8 of 100 points: Model quality 8.3/45, Memory fit 0.0/25, Speed 0.0/15, Memory use 0.0/15 GGUF · part 1 of 9 (opens in a new tab)
Q4_K_M 49.3 GB 21.4 GB — Won't run 9 ptsWon't run (F) · 9 of 100 points: Model quality 9.4/45, Memory fit 0.0/25, Speed 0.0/15, Memory use 0.0/15 GGUF · part 1 of 12 (opens in a new tab)
Q5_K_M 56.6 GB 21.4 GB — Won't run 9 ptsWon't run (F) · 9 of 100 points: Model quality 9.6/45, Memory fit 0.0/25, Speed 0.0/15, Memory use 0.0/15 GGUF · part 1 of 14 (opens in a new tab)
Q6_K 64.6 GB 21.4 GB — Won't run 9 ptsWon't run (F) · 9 of 100 points: Model quality 9.8/45, Memory fit 0.0/25, Speed 0.0/15, Memory use 0.0/15 GGUF · part 1 of 16 (opens in a new tab)
Q8_0 82.1 GB 21.4 GB — Won't run 9 ptsWon't run (F) · 9 of 100 points: Model quality 9.9/45, Memory fit 0.0/25, Speed 0.0/15, Memory use 0.0/15 GGUF · part 1 of 21 (opens in a new tab)
F16 150 GB 21.4 GB — Won't run 9 ptsWon't run (F) · 9 of 100 points: Model quality 9.9/45, Memory fit 0.0/25, Speed 0.0/15, Memory use 0.0/15 GGUF · part 1 of 42 (opens in a new tab) Original weights (opens in a new tab)

Memory figures assume 8K of context. Longer conversations or documents grow the KV cache.

Hardware that can run it

Models that do run on the Apple M2 Pro (32 GB)

Estimates come from published hardware specs and our open formulas, not from running the model on your machine. Real speed varies with runtime, drivers and settings. Numbers marked “Measured” come from a linked benchmark.