Llama 3.1 405B Instruct on AMD EPYC 7002 / 7003 series NAS (512 GB)

Can the AMD EPYC 7002 / 7003 series NAS (512 GB) run Llama 3.1 405B Instruct?

Barely: it runs very slowly

Very slow. At Q6_K it needs about 375 GB of 471 GB usable, with an estimated speed of 0.2 tok/s.

Best quant: Q6_K
Generation speed: 0.2 tok/s
Prompt processing: 1.0 tok/s
First token (1K prompt): 1,039.0 s
Largest safe context: 128K

Best app to run it on the AMD EPYC 7002 / 7003 series NAS (512 GB)

On Linux

Ollama

Command line + local API · runs on llama.cpp (ggml), MLX (Apple silicon, preview)

One command with Ollama’s own build of this model.
Serves an OpenAI-compatible API that other apps and coding tools can use.

ollama run llama3.1:405b-instruct-q6_K

llama.cpp Usually the first to support new model architectures.
KoboldCpp

How we choose: the files published for this model, which apps run in a container on a NAS without a graphics card (models run on its processor), and whether the model fits fully in the memory models can use. Details.

Download Llama 3.1 405B Instruct

Recommended for the AMD EPYC 7002 / 7003 series NAS (512 GB): Q6_K. Every other quantization has its own download link in the table below.

Quickest · Ollama

One command downloads a ready-to-run version and starts a chat.

Get Ollama at ollama.com/download (opens in a new tab) · model page (opens in a new tab)

ollama run llama3.1:405b-instruct-q6_K

Quantized files · GGUF

Works in LM Studio, llama.cpp, Jan and Ollama. No sign-in needed.

huggingface.co/MaziyarPanahi/Meta-Llama-3.1-405B-Instruct-GGUF (opens in a new tab)

ollama run hf.co/MaziyarPanahi/Meta-Llama-3.1-405B-Instruct-GGUF

Original weights · Hugging Face

Full-precision files from Meta, for fine-tuning, vLLM, Transformers.

huggingface.co/meta-llama/Llama-3.1-405B-Instruct (opens in a new tab)

Free Hugging Face account needed: request access on the model page, and Meta approves it (usually within minutes to a few hours).

Official repo · GitHub

Reference code, inference scripts and docs from Meta. The weights themselves download from Hugging Face.

github.com/meta-llama/llama-models (opens in a new tab)

Meta’s official Llama repo: model cards, prompt formats and download tools.

git clone https://github.com/meta-llama/llama-models

Links checked 1 day ago against Hugging Face, Ollama and GitHub.

How it’s rated

Quality 71Great quality (A) · 71 of 100: how capable the model is at Q6_K, whatever it runs on. Match score 73/100 (quality, fit, speed and memory use) sets the ranking.: How capable the model itself is at Q6_K, from its editorial quality tier scaled by the quantization or precision. It’s the same on any hardware that runs this variant. Scale: A+ 85+ · A 70+ · B 55+ · C 40+ · D under 40.
Runs Very slow: How well it runs on the AMD EPYC 7002 / 7003 series NAS (512 GB): speed, capped by how well it fits in memory. Runs great: 30+ tokens/s (or near the image, video or decision speed target) · Runs well: 10+ tokens/s · Slow: 3+ tokens/s · Very slow: under 3 · Won’t run: doesn’t fit even with offload. A tight fit or RAM offload caps it at Runs well; heavy offload caps it at Slow.

Match score

To order lists, each result also gets a match score out of 100 from four parts. It favors the most capable model that still runs well.

Model qualityEditorial quality tier of the model, scaled by the quantization or precision used.	32.1 / 45
Memory fitFull marks when the model fits in the share of the NAS’s memory that models can use (the rest stays with the NAS system and its storage services); fewer when it goes past that limit.	25.0 / 25
SpeedGeneration speed against a 40 tokens/s target for LLMs, or render time against a target for image and video.	1.2 / 15
Memory useRewards using the memory you have, so a bigger, better variant beats a tiny one that leaves most memory idle.	15.0 / 15
Match score	73.2 / 100

The match score orders results; it is not shown as a grade. Quality and Runs are the two ratings in the tables.

Every quantization on the AMD EPYC 7002 / 7003 series NAS (512 GB)

Quant	Memory needed	Available	Speed	Runs	Quality	Download
`Q2_K`	205 GB	471 GB	0.6 tok/s	Very slow	50Fair quality (C) · 50 of 100: how capable the model is at Q2_K, whatever it runs on. Match score 59/100 (quality, fit, speed and memory use) sets the ranking.	GGUF · part 1 of 9 (opens in a new tab)
`Q3_K_M`	241 GB	471 GB	0.4 tok/s	Very slow	60Good quality (B) · 60 of 100: how capable the model is at Q3_K_M, whatever it runs on. Match score 65/100 (quality, fit, speed and memory use) sets the ranking.	GGUF (Q3_K_S) · part 1 of 9 (opens in a new tab)
`Q4_K_M`	290 GB	471 GB	0.3 tok/s	Very slow	68Good quality (B) · 68 of 100: how capable the model is at Q4_K_M, whatever it runs on. Match score 71/100 (quality, fit, speed and memory use) sets the ranking.
`Q5_K_M`	331 GB	471 GB	0.3 tok/s	Very slow	69Good quality (B) · 69 of 100: how capable the model is at Q5_K_M, whatever it runs on. Match score 72/100 (quality, fit, speed and memory use) sets the ranking.
`Q6_K`	375 GB	471 GB	0.2 tok/s	Very slow	71Great quality (A) · 71 of 100: how capable the model is at Q6_K, whatever it runs on. Match score 73/100 (quality, fit, speed and memory use) sets the ranking.
`Q8_0`	473 GB	471 GB	—	Won't run	72Great quality (A) · 72 of 100: how capable the model is at Q8_0, whatever it runs on. Match score 9/100 (quality, fit, speed and memory use) sets the ranking.
`F16`	854 GB	471 GB	—	Won't run	72Great quality (A) · 72 of 100: how capable the model is at F16, whatever it runs on. Match score 9/100 (quality, fit, speed and memory use) sets the ranking.	Original weights (opens in a new tab)

Memory figures assume 8K of context. Longer conversations or documents grow the KV cache.

Other hardware that runs it

68Good quality (B) · 68 of 100: how capable the model is at Q4_K_M, whatever it runs on. Match score 80/100 (quality, fit, speed and memory use) sets the ranking. AMD Instinct MI350X Q4_K_M · 20.8 tok/s · Runs well (tight fit)
60Good quality (B) · 60 of 100: how capable the model is at Q3_K_M, whatever it runs on. Match score 78/100 (quality, fit, speed and memory use) sets the ranking. NVIDIA GB300 Grace Blackwell Ultra Desktop Superchip Q3_K_M · 27.8 tok/s · Runs well (tight fit)
60Good quality (B) · 60 of 100: how capable the model is at Q3_K_M, whatever it runs on. Match score 77/100 (quality, fit, speed and memory use) sets the ranking. AMD Instinct MI325X Q3_K_M · 20.2 tok/s · Runs well
50Fair quality (C) · 50 of 100: how capable the model is at Q2_K, whatever it runs on. Match score 76/100 (quality, fit, speed and memory use) sets the ranking. NVIDIA B200 Q2_K · 39.7 tok/s · Runs well (tight fit)
50Fair quality (C) · 50 of 100: how capable the model is at Q2_K, whatever it runs on. Match score 72/100 (quality, fit, speed and memory use) sets the ranking. AMD Instinct MI300X Q2_K · 22.7 tok/s · Runs well (tight fit)
50Fair quality (C) · 50 of 100: how capable the model is at Q2_K, whatever it runs on. Match score 66/100 (quality, fit, speed and memory use) sets the ranking. Apple M3 Ultra (256 GB) Q2_K · 3.5 tok/s · Slow (tight fit)

Estimates come from published hardware specs and our open formulas, not from running the model on your machine. Real speed varies with runtime, drivers and settings. Numbers marked “Measured” come from a linked benchmark.